Neuromodulatory role of Bacopa monnieri on oxidative stress induced by postnatal exposure to decabromodiphenyl ether (PBDE -209) in neonate and young female mice
نویسندگان
چکیده مقاله:
Objective(s):Bacopa monnieri (BM),a traditional ayurvedic medicine,is a well-known memory enhancer. We have explored the role of BM against decabrominated diphenyl ether (PBDE-209)-induced alterations in neonate and young female mice. Materials and Methods: Mice were orally administered with B. monnieri at the doses of 40, 80 or 120 mg/kg body weight along with PBDE-209 (20 mg/kg body weight) from postnatal day (PND) 3-10. Levels of malondialdehyde, protein carbonyl and activities of superoxide dismutase and glutathione peroxidase were measured at both ages. The correct choices and reference/working memory errors of young mice were evaluated by Morris water and radial arm maze. Results: The results showed that BM at the dose of 120 mg/kg significantly (P
منابع مشابه
neuromodulatory role of bacopa monnieri on oxidative stress induced by postnatal exposure to decabromodiphenyl ether (pbde -209) in neonate and young female mice
objective(s):bacopa monnieri (bm),a traditional ayurvedic medicine,is a well-known memory enhancer. we have explored the role of bm against decabrominated diphenyl ether (pbde-209)-induced alterations in neonate and young female mice. materials and methods: mice were orally administered with b. monnieri at the doses of 40, 80 or 120 mg/kg body weight along with pbde-209 (20 mg/kg body weight) f...
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عنوان ژورنال
دوره 17 شماره 4
صفحات 307- 311
تاریخ انتشار 2014-04-01
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